PERSSILAA, a FP7 funded European project, develops and validates a new service model, to screen for and prevent frailty in community dwelling older adults, integrating nutrition, physical and cognitive function. PERSSILAA develops remote service modules for screening, monitoring and training. Screening – easy to use tools to get an overall picture of a person’s health status. Monitoring – unobtrusive monitoring of everyday functioning. Training – remotely available health promotion programs. PERSSILAA innovates the way our care services are organized from fragmented reactive disease management into preventive personalized services offered through local community services, supported by a proactive team of caregivers and health professionals and integrated into existing healthcare services. PERSSILAA realizes a technical service infrastructure to support these multiple services and users in an efficient, reliable, easy to use way and therefore works on gamification, interoperability and clinical decision support. PERSSILAA builds on activities within the European Innovation Partnership on Active and Healthy Aging and on results of various earlier European projects. In the project, there is continuous end- user involvement and evaluation with 350 older adults in real implementation environments in Enschede (the Netherlands) and Campania region (Italy) to ensure increasing system efficiency and easy end-user acceptance. Outcomes focus on daily activities, quality of life and risk of hospitalization. PERSSILAA builds business models for sustainable implementation and develops recommendations for European guidelines.